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The findings, published in the American Journal of Physiology, show e-cigs and refills are not well regulated and their long-term effects on health are unknown

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Most medical organizations, including international organizations such as the WHO and those in the US, feel there is insufficient evidence to routinely recommend electronic cigarettes for use in smoking cessation [4] other medical organizations, particularly British ones, state e-cigarettes are a reasonable third-best alternative for smokers who are unable to quit

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The lower esophageal sphincter (LES) is a muscle that normally prevents stomach contents from flowing backward