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In extreme situations, and only after extensive medical consultation, some patients have the offending olfactory bulb (we have one for each nostril see illustration above) removed by surgery, but this is a very risky procedure and would lead to permanent loss of smell for that nostril

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All subjects were asked to abstain from smoking, coffee, and other foods or beverages containing caffeine (e.g., tea, cola, cacao, guarana) for a wash-out period of at least 12 hours before examinations