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Similarly, 4-aminobiphenyl, metabolized by hepatic CYP1A2, produces reactive intermediates that form DNA adducts in hepatocytes, increasing the mutational burden [27]

During the flowering phase of the growing cycle, when buds are still attached to the branches of living plants, excess humidity and lack of airflow can cause mould to proliferate

When a cigarette is smoked, chemicals in the smoke stick to surfaces and dust for months after the smoke is gone

Establishes penalties for noncompliance, including license suspension and revocation

Data availability The datasets analyzed during the current study are publicly available in the NCBI Gene Expression Omnibus (GEO) repository under accession number GSE309416 ( The Nicotiana tabacum genome sequence was obtained from the Sol Genomics Network ( which is publicly accessible

We were looking at Brian Epstein, who had a little butt, the tiniest little butt, so he looked like a tramp smoking a dog-end, which we had only ever done when we were poor before