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Published online May 16, 2023

Last updated 26 January 2026 Not yet

Smoking is perceived as a coping mechanism for anxiety and stress, but in turn, it causes a plethora of other physical and emotional symptoms, which can lead to an increase in stress levels

Furthermore, reduced expression of the arginine methyltransferase coactivator-associated arginine methyltransferase 1 (CARM1) in COPD bronchial epithelial cells is associated with increased senescence, and impaired club cell regeneration and epithelial repair, possibly through altered histone methylation of cell cycle and differentiation genes (184, 185)

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