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While potentially less harmful overall, nicotine-containing e-cigarettes may still affect esophageal sphincter function, though more research is needed to fully understand their impact on GERD

But in December 2018, Juul sold 35% of the companys ownership to tobacco company Altria

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We did not do a subgroup analysis because this is cross-sectional research

In contrast, solution from nicotine-free vape liquids (strawberry poptart and apple watermelon flavors) was shown to inhibit the activity of CYP2A6 (163).Together, these findings demonstrate both CYP isoform-specific and direction-specific effects following exposure to different electronic cigarette solutions

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