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doi:10.1136/bmjgh-2018-000873

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FIGURE 3 FIGURE 4 For between-group comparisons in smokers, we observed significant brain region atrophy in the subgroup of heavy smokers compared to light smokers, mainly in GM areas of precuneus, inferior frontal gyrus, insula, STG and cerebellum anterior lob, and in WM areas of cerebellum anterior lobe ( Table 4 )

Guarantee lower health risks in real-world use, because smoking behavior and total exposure still matter

If NSAIDs or alcohol are the causes, stopping or reducing their use can help

Even people who smoke fewer than five cigarettes per day may show early signs of cardiovascular disease