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The research showed that nicotine exposure decreased electrically-stimulated dopamine release across various stimulation frequencies, and these changes in dopamine sensitivity predict individual variations in vulnerability to substance use disorders

There exists a drug called Varenicline also known as Chantix which specifically targets the nicotine receptors in the brain which reduces the satisfaction that smoking gives you and lowers withdrawal symptoms

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This triggers the release of several neurotransmittersincluding dopamine, the chemical responsible for pleasure and reward

However, it is often difficult to answer these questions due to a lack of evidence regarding their impact