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Custom Shop reproduction [edit] In November 2006, Fender announced a limited run of 275 Blackie reissues by the Fender Custom Shop, identical to the original

It is also linked to other serious conditions, including heart disease, stroke, type 2 diabetes, asthma and dementia, and can affect sexual performance, fertility and pregnancy

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As one review stated, Nicotine is the addictive chemical in tobacco smoke, but its involvement in smoking-related harm (outside pregnancy) is very small, if any, compared to cigarette smoking. Another systematic review pointed out that nicotine can have a variety of potential health effects, from raising ones cardiovascular risk to causing birth defects in pregnant women

But the RSPH says more services should follow the example of those in Leicester and north-east England in offering behavioural support to those wanting to quit tobacco and using e-cigarettes to try to do so