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As a result, great caution and hesitation should remain concerning e-cigarette use until its health risk profile is better established. After completing this review, the researchers conclude that, with respect to cardiovascular disease, the risks from e-cigarettes cannot be said to be less than they are from smoking cigarettes until more research can show this to be the case

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In the context of the European research project Addiction and Lifestyles in Contemporary Europe Reframing Addictions Project, the aim of this research was to provide a comparative risk assessment of drugs using a novel risk assessment methodology, namely the Margin of Exposure (MOE) method

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