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Since SIRT6 has context-dependent (dose-, tissue-, model-dependent) roles in the brain, these findings should be viewed as a plausible, theoretical mechanistic pathway

"This is important as our population gets older , because aging and smoking are both risk factors for dementia," noted Bierut

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Several studies have shown evidence of increased oxidative stress in patients with COPD both locally and systemically, particularly during exercise (Couillard et al