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If POB-DNA adducts and related adducts remain unrepaired by either evading or overwhelming healthy cellular repair systems, the result can be miscoding leading to DNA mutations in somatic cells

Journal of Thoracic Disease, 12 (7), 38663876

These pathogens mainly include Aspergillus , Penicillium , and Fusarium , which can utilize various organic compounds provided by cigar tobacco as energy and nutritional sources

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Equipment typically required (per demo): Large conical flask Universal indicator solution 2 pieces of bent glass tubing with relevant holed bungs Retort stands, bosses and clamps Wider glass tube with holed bungs Ceramic/cotton wool Water powered filter pump (or hand pump or gas syringe) Cigarette holder (or plastic tube) Cigarette Matches This demonstration has been the subject of much discussion with the recent smoking ban coming into force in the UK