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Bruce Springsteen participated in the recording of three of the album's tracks

Our work aims to understand what makes women more susceptible to nicotine use disorder to reduce the gender disparity in treating nicotine addiction. The researchers found that the sex hormone estrogen induces the expression of olfactomedins, proteins that are suppressed by nicotine in key areas of the brain involved in reward and addiction

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However, tobacco smoking is so addictive, and often bound to social and environment contexts, that even low-level smokers experience a loss of autonomy over their smoking behaviour [19, 20], meaning they also struggle to quit [21, 22]