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Nicotine, a well-known component of cigarette smoke, also alter metabolic pathways particularly by interfering with Organic Cation Transporters (OCTs) in vitro (Urakami et al., 1998

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Biliary Excretion: The liver secretes some drug metabolites into bile, which is then excreted in the feces

A decade ago, we started asking every patient if they smoke and if theyre exposed to secondhand smoke

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