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It is noteworthy that the risk of peripheral arterial disease was more than double in patients with diabetes who smoke at RR = 2.15

Neural substrates of smoking and reward cue reactivity in smokers: a meta-analysis of fMRI studies

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To reduce risk during outdoor work, the Occupational Safety and Health Administration recommends scheduling frequent rest breaks in shaded or air conditioned environments

By 1640, tobacco was the predominant cash crop

It would appear that the impact of standardized packaging may be affected by the detail of the regulations such as whether they ban descriptors, such as smooth or gold, and control the shape of the tobacco pack. Co-author Jamie Hartmann-Boyce, from the Cochrane Tobacco Addiction Group, Oxford, UK, added: Our evidence suggests that standardized packaging can change attitudes and beliefs about smoking, and the evidence we have so far suggests that standardized packaging may reduce smoking prevalence and increase quit attempts