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In the smoke-exposed cells, the group found that DNA damage responses were increased due to reactive oxygen species just 10 days after the beginning of the experiment

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Luther Terry and to get behind his call for immediate remedial actions to curb cigarette consumption, the American Medical Association instead signed a $10 million contract with six cigarette manufacturers to support independent research that it claimed was needed for the identification and removal of the harmful components in tobacco. The tobacco industry had been using this exact language since the first large studies linking smoking and lung cancer were published in the early 1950s