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29 demonstrated that exposure to 10% cigarette smoke extract had a significant effect on endothelial arginine and proline metabolism, resulting in the reduction of intracellular arginine, N-hydroxy-l-arginine, and citrulline

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Smoking with a sore throat is generally not advisable, as it may worsen irritation and delay healing

Many smokers can switch to vaping and use e-liquid with a high nicotine rating, then gradually reduce the strength