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How Smoking and Nicotine Damage Your Body American Heart Association This Is What Happens When You Smoke , Every puff exposes your body to thousands of chemicals, many of which are harmful., Your lungs become damaged over time, Your heart has to work harder, Cigarette smoke does not stop at your lungs. Some harmful chemicals enter your bloodstream, including carbon monoxide, a gas that can reduce how much oxygen your blood carries. When your blood carries The roles and regulatory mechanisms of cigarette smoke constituents in vascular remodeling ScienceDirect Yes, smoking hookah can lead to carbon monoxide poisoning Carbon monoxide poisoning: Another reason not to smoke Poison Control

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