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The researchers found that the mean HbA1c change was significantly greater with cagrilintide-semaglutide (2.4 mg each) versus semaglutide 2.4 mg (1.91 versus 1.75 percentage points)

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Interestingly, in the Npc1 mouse model, the levels of infiltrating mononuclear cells are lower in the cerebellum relative to other brain regions, with no significant loss of neurons or oligodendrocytes

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