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Like with other cannabis products, one of the most concerning aspects of using hash is that it can lead to addiction

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It requires a higher heat to burn, so it can irritate the lungs and throat upon exposure

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Experimental, immunologic, and systems-level studies indicate that cigarette smoking promotes immune phenotypes resembling accelerated aging, including contraction of nave lymphocyte pools, expansion of senescent T-cell populations, disruption of regulatory signaling pathways, and persistent remodeling of adaptive immunity