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Prevalence of oral cancer in adolescents related to Areca (betel) nut chewing, using tobacco and other additives in Saipan, Northern Marianas Islands: a review of literature

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(with co-authors Sally Satel and Lee Jussim) argued in a recent article that over time, IRBs have become more restrictive and intolerant of even minor and well-understood (and consented-to) risks (well worth a read): The cases correspond loosely to distinct eras in history that have been termed by Moreno, Weak Protectionism, Moderate Protectionism, and Strong Protectionism. We believe we have now descended into an era of Hyper-Protectionism in which the costs to science far outweigh the benefits to protection of human subjects