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It is a popular drug among the younger generation and if abused early on, it can cause permanent IQ loss, damage to brain development and long-term health issues

Adrenal insufficiency-greatest potential caused by high potency glucocorticoids with long duration of action (associated symptoms include: arthralgias, buffalo hump, dizziness, life-threatening hypotension, nausea, severe tiredness or weakness), amenorrhea, postmenopausal bleeding or other menstrual irregularities, decreased carbohydrate and glucose tolerance, development of cushingoid state, diabetes mellitus (new onset or manifestations of latent), glycosuria, hyperglycemia, hypertrichosis, hyperthyroidism (See WARNINGS: Endocrine), hypothyroidism, increased requirements for insulin or oral hypoglycemic agents in diabetics, lipids abnormal, moon face, negative nitrogen balance caused by protein catabolism, secondary adrenocortical and pituitary unresponsiveness (particularly in times of stress, as in trauma, surgery or illness) (See WARNINGS: Endocrine), suppression of growth in pediatric patients

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DOI: 10.1186/s12889-019-7546-y 4

They have been used on every American space mission since they debuted on Apollo 7, and there is no shortage of them aboard the ISS