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Abbreviations Apoe: Apolipoprotein E E-cigarette: Electronic cigarette FDA: Food & Drug Administration HPHC: Harmful or potentially harmful chemical NNAL: 4-Methylnitrosamino)-1-(3-pyridyl)-1 butanol NNN: N 1 -Nitrosonornicotine Nrf2: Nuclear factor erythroid factor 2 RRP: Reduced risk product TEER: Trans-epithelial electric resistance References WHO

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[DOI] [PMC free article] [PubMed] [Google Scholar] [84].Knutson CG, Akingbade D, Crews BC, Voehler M, Stec DF, Marnett LJ, Metabolism in vitro and in vivo of the DNA base adduct, M1G, Chem Res Toxicol, 20 (2007) 550557