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Cannabinoids exert their effects primarily through activation of the ECS, which consists of the cannabinoid receptors CB 1 and CB 2 , endogenous ligands such as anandamide and 2-arachidonoylglycerol (2-AG), and enzymes responsible for ligand synthesis and degradation (50)

Regulation has been both a protective force and a marketshaping force, sometimes enabling harm reduction and sometimes undermining it

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Last September the police chief handed out a $81 fine for littering