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The long term safety of their use also remains unclear

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Drop for drop, that would make nicotine more deadly than strychnine (75mg), diamond back rattlesnake venom (100mg), arsenic (200mg) or cyanide (500mg)

over the past 40 years have had a filter tip, it would be difficult to simply ban them, as consumers have come to accept the filter as an integral part of the product design

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In 2005, the Harm Reduction Journal published a study from the University of Colorado titled Cannabis and tobacco smoke are not equally carcinogenic. The authors explained that: Both [tobacco and marijuana] smoke contain carcinogens and particulate matter that promote inflammatory immune responses that may enhance the carcinogenic effects of the smoke