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Effect of Smoking on Blood Pressure and Resting Heart Rate Circulation: Cardiovascular Genetics Smoking: A Direct Hit to the Heart Every puff of a cigarette is a direct challenge to your cardiovascular system. Beyond the lungs, the chemicals in tobacco smoke enter your bloodstream Smoking does not only affect your lungs. It can also put pressure on the heart and damage the blood vessels. Nicotine can make the heart beat faster and tighten blood vessels. Over How Smoking Affects Your Heart Smoking and Your Heart The Texas Heart Institute do cigarettes slow your heart rate do cigarettes make your heart beat faster How to Stop

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