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In terms of the addiction, I think it's more in circumstantial associations rather then the biochemical pathways

*Correspondence: Shanshan Su, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Using apoptosis assays and single-cell time-lapse imaging, we found that the REN, VMC23, and MSTO-211H cells exhibited either enhanced G1 arrest, cell death, or abnormal mitotic division

At the same time, these dont absolve nicotine pouches from faults, as users exhibit side effects when abusing the substance as well