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And so Ive really started wondering if they are changing the cells that surround the cancer. In the eighties, not long after Balmain started researching cancer, the field was dominated by a step-by-step multi-hit model of carcinogenesis

We calculated the duration of smoking cessation from the onset of quitting to the relapse of smoking, occurrence of study outcomes, or the end of follow-up (Table S1 in the Supplementary Appendix)

But cell studies are just one piece of the puzzle

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