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THC binds to and activates CB1 receptors, part of the endocannabinoid system, which are located in the stomach, small intestine, and parts of the brain that monitor food intake and enhance eating pleasure

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It found that the protein alpha-synuclein, which accumulates in people with Parkinsons, aggravates oxidative stress, mitochondrial dysfunction and cell death when exposed to cigarette aerosol extract

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Furthermore, there is growing evidence of the relationship between air pollution and lung cancer among never smokers [48, 49]