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For example, scientists gave nicotine (by injections) to adolescent rats and found the same increased number of nicotinic receptors in rat brains as seen in human brains

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Pipe tobacco took a back seat to this more modern style of smoking

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Tobacco & Vaping Tobacco products include cigarettes, cigars, pipe tobacco, water pipes (hookahs), snuff, chewing tobacco, electronic cigarettes (E-cigarettes), and vaping devices

O'Connor RJ, Flaherty BP, Edwards BQ, Kozlowski LT: Regular smokeless tobacco use is not a reliable predictor of smoking onset when psychosocial predictors are included in the model