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Professor Dame Sally Davies, the chief medical officer, said that while many were aware of the damage smoking does to the heart and lungs, they were less likely to know about the damage that is done to the rest of the body, which she compared to rotting it from the inside out

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And this was a thing that felt both offensive and, actually, maybe he had the kind of hubris or self-belief to think that he could do something about it

Authors contributions OMM, UL, LB and MRM were responsible for the conception and design of the trial, and the plan for the analysis of the data

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