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The National Institute of Medicine predicts that by increasing the age of sale for tobacco products to 21, there is a significant reduction in the number of adolescents and young adults who start smoking, reduced deaths from smoking and an immediate improvement of the health of adolescents and young adults

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Adult smokers prefer tobacco and botanical flavors in disposables for convenience and similarity to traditional smoking, while reusables see moderate use among experienced or cost-conscious users

Nicotine can temporarily boost mood and focus, but repeated use leads to dependence and mood swings when nicotine levels drop

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However, the shared genetic vulnerability hypothesis does not provide a way of identifying the direction of the association between smoking and schizophrenia (Chen Reference Chen, Bacanu and Yu2016)