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BMC Oral Health 24(1):889 SAMHSA (Substance Abuse and Mental Health Services Administration) (2022) Key substance use and mental health indicators in the United States: results from the 2021 National Survey on Drug Use and Health

Reports from the first European explorers and conquistadors to reach the Americas tell of rituals where native priests smoked themselves into such high degrees of intoxication that it is unlikely that the rituals were limited to just tobacco

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Investigators said the difference may be due to the way that marijuana is smoked and the fact that marijuana smoke enters the lungs unfiltered