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Whats more, he added, with some evidence that nicotine could play a role in the development of diabetes, there may be down sides to the use of such devices, even if they do help smokers keep the weight off

Most interestingly, there is still not much known about the role and regulation of HIFs under normoxic conditions beyond cancer cells and our findings provide important data on the regulation of glycolysis under the control of HIFs under normoxic conditions

Environ Sci Technol 44(10):39473955