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JUUL really doesnt need any introduction given its still the worlds largest selling vape product, with reports of upwards of $3.5 billion sales per year wow Despite those huge sales, the company has been dogged by controversy from both members of the wider vape community and indeed politicians and anti-vape groups

Nevertheless, the long-term cardiovascular safety of e-cigarettes remains unclear and currently represents an area of active investigation

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Details on each, including the studys design, data sources, number of participants, length of follow-up, confounders adjusted for in the input data and bias covariates included in the doseresponse risk model, can be found in Supplementary Information 2 and 3

Because the Michigan tax rate remained above Indiana and Wisconsin during the sample period, we would expect to observe cross-border shopping by Michigan residents in these two states

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