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Truth is, calling satisfaction of dopamine pathway wanting pleasure is like saying that it feels good to stop pounding your thumb with a hammer

The lifetime risk of developing stomach cancer is higher in men

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So Selye began to suggest that subjecting an animal to prolonged stress led to tissue changes and physiological changes with the release of certain hormones, that would then cause disease and ultimately the death of the animal." And so the idea of stress and it's potential costs to the body was born