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A growing body of research suggests that the dysregulation of the nicotinic cholinergic system is responsible for modulating the sensory processing input processes, which accounts for the control issues that are typical of ADHD [73] nAChRs also have a role in the regulation of neurotransmitters including dopamine and serotonin

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3537 The ratio of 3HC to cotinine in plasma or saliva can be used as a reliable noninvasive phenotypic marker for CYP2A6 activity

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