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Illicit trade can be undertaken both by illicit players who are not registered with relevant government agencies, and legitimate entities whose business operations are contrary to applicable laws and regulations

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That means two products sitting side by side on a shelf, both saying THC-free, could be completely different

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People have different reasons for smoking, it can be simply out of trend or fashion or it can be addiction

Ethics declarations Ethics approval and consent to participate The study was approved by the Ethics Committee of the Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences (0282013), and all participants written informed consent