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This step-wise approach may lower adverse consequences associated with risky substance use behaviors (including smoking) while maintaining engagement and motivation as a person progresses through the stages of change 36

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The questionnaire included general demographic information, family status, reproductive history, medical disease, behavioral habits, diet habits, injury, depressive symptoms, self-care ability, and cognitive function

[21] [22] A 2021 longitudinal study conducted among populations of HIV-positive and HIV-negative adults found that smoke-related carcinogenic toxicants and biomarkers detected in tobacco smokers were also detected in exclusive cannabis smokers, including carbon monoxide (CO), polycyclic aromatic hydrocarbons (PAHs), aldehydes (such as acrolein), acrylonitrile and acrylamide metabolites, but exposures are lower compared with tobacco or dual smokers

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N Engl J Med 362(24):22952303 Hoffmann D, Hoffmann I (1998) Chemistry and toxicology