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Differential in vivo effects of whole cigarette smoke exposure versus cigarette smoke extract on mouse ciliated tracheal epithelium

With 65%RH being required to maintain the tobaccos moisture content, any air introduced with a relative humidity of 24% would lead to moisture loss from the tobacco without correct humidification

Vitamin D Research has shown that people with emphysema tend to have lower levels of vitamin D in their blood than healthy individuals

Notably, the chemical constituents of e-cigarettes, including nicotine salts, aldehydes, and ultrafine particles, provoke bronchial epithelial irritation and oxidative stress, thereby amplifying epithelial injury and sustaining pulmonary inflammation (55)

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This may lead to a long-term cough