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Research reported in this publication was supported by NHLBI and FDA Center for Tobacco Products (CTP)

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We hypothesized that genes associated with nicotine exposure paradigms in model organisms will: (1) contribute to the heritability to human tobacco consumption, (2) be enriched for genes associated with human tobacco consumption, and (3) aid in the prediction of a polygenic score of human tobacco consumption in an independent sample (see Fig

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