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For example, the inhibition of histone deacetylases or demethylases interferes with the chromatin modifications that maintain DTP cells in a drug-tolerant state, such as the retention of closed or repressed chromatin at pro-apoptotic loci, thereby restoring susceptibility to drug-induced apoptosis (55)

When averaging together information from more than 100,000 people, the presence of an Lp(a) genetic variant caused an average decrease in lifespan of 1.5 years.[ref] This doesnt mean everyone with high Lp(a) dies early

86 SonninenT.-M.HmlinenR

The primers used for the construct preparation are listed in Table S1

Autophagy can prevent toxic accumulation of cell waste, protect organelles and maintain cell survival

Oxidative Med Cell Longev 2018:8152373