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Harvard research shows that lowering the nicotine content of cigarettes reduces dependence and makes quitting easier .[5] They also found that e-cigarettes with added nicotine foster greater dependence than any other ingredient.[6] The Science is Clear: Nicotine Is Addictive There is overwhelming evidence that nicotine is addictive, regardless of the source

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In the eleventh season, his soliloquy reveals his full birth name to be Carl Gerhard Busch , though whether he has any meaningful "real" identity in his later life outside of the Smoking Man persona is unclear

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While both use liquid to store the nicotine, freebase nicotine (used in e-liquids) and nicotine salt (used in pods/cartridges) are different