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Among included participants, smokers have smoked at least 20 cigarettes/ day or more for at least one year, plus alcohol drinkers were drinking at least 40 g of alcohol daily for at least one year

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While the FDAs cessation focus is primarily in regulating and approving cessation products, Section 918 of Family Smoking Prevention and Tobacco Control Act also expressly charged the FDA with submitting to Congress a report on how best to promote and encourage non-nicotine-based treatments, with an aim of achieving total abstinence of tobacco use. Despite up to 75-80 percent of ex-smokers quitting cold turkey,[3] the FDA chose to read Section 918 so as to totally abrogate responsibility for investigating, understanding, promoting or encouraging successful abrupt nicotine cessation

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The cigarette brands covered originate from countries like the United States, United Kingdom, India, and Canada

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