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When questions arose about the ill-effects of a very popular product like tobacco, they usually focused on two key themes: 1) how bad is the problem (i.e., the absolute risk) and 2) what can be done to reduce the risk without giving up such products (i.e., the prospects for harm reduction [5])

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Thus, the current sample included herein were those who did not attempt to stop smoking, or attempted to quit but were unsuccessful, which could have implications (e.g., they were more dependent on nicotine, they may have been less motivated to do so, may have been more likely to have used cannabis and/or alcohol and/or have depressive symptoms)