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For sensitivity analysis, three different methods were applied: convergence testing during the probabilistic simulation, application of a factor to consider drug tolerance and comparison with human toxicological thresholds for some of the agents

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On the other hand, THC cigarettes typically contain Delta-9 THC or Delta-8 THC, both psychoactive compounds that can induce a euphoric high. For example, THC may alter perception or mood [7]

"The whole mission is to decrease harm from smoking, which is not from the nicotine per se, but all the carcinogens and other chemicals that are in tobacco smoke," said Lazarus, senior author on the study published in the journal Chemical Research in Toxicology