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Intravenous use can be very effective, and doesn't cause diarrhea by this route, but this agent must be given extremely carefully, since an error in dosing can shut down the bone marrows production of blood cells, and potentially be fatal

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For operators of flue-cure tobacco, cutting operational costs such as energy to flue leaves and employment is crucial to stay competitive in the business

Decreased or irregular urination patterns from impaired kidney perfusion