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[42] [43] Smokers are 3040% more likely to develop type 2 diabetes than non-smokers, and the risk increases with the number of cigarettes smoked

The high prevalence of exposure to SHS in a scenario with an increasing number of smokers and the harmful associations with conditions of global relevance warrant policy focus even with weak evidence supporting the analyses when compared to other less prevalent risks associated with rare or less severe outcomes and strong supporting evidence

In most cases, the answer is 20 cigarettes

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"But the key is to not get discouraged

These contentions, however, stand in stark contrast with potential beneficial effects of nicotine or nicotinic agonists in a variety of diseases [13, 37], including COVID19 [18, 19, 38]