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During the chronic phase, inflammatory cells are continuously recruited and release inflammatory mediators, such as proteases (e.g., MMPs and neutrophil elastase), chemokines, cytokines, and ROS

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Some of the diseases that are known to potentially have an adverse effect on the fetus include: diabetes, cytomegalovirus, toxoplasmosis, rubella, varicella, hypothyroidism, and Strep B

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