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2016;81 Suppl 2:S82-S92

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Several analyses report an inverse association between current smoking and SARS-CoV-2 infection or seropositivity, while methodological reviews emphasize the potential role of bias and unmeasured confounding, including misclassification of smoking status, selection bias, and differences in healthcare-seeking behavior ( Across diverse study designs and populations, an inverse association confined largely to current smokers has been reported in several quantitative analyses

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This leads to lower fertilization rates, as fewer eggs successfully unite with sperm to form embryos

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