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Some devices deliver higher concentrations of nicotine than others due to the different quantities used in the various brands

30 Nicotine is metabolized primarily to cotinine, which is further metabolized to trans-3-hydroxycotinine (3HC), catalyzed by the liver cytochrome P450 2A6 enzyme

Violations of FDA's rules regarding unauthorized claims were rare (one post highlighted modified risk)

for example, past campaigns used slogans like Commit to Quit and Say Yes to Life, No to Tobacco, emphasising that quitting is a life-saving, positive step